Screening for Chronic Kidney Disease in Relatives of Hemodialysis Patients

Jocélia Martins Cavalcante Dantas ,Wellyson Da Cunha Araújo Firmo ,Marcos Tadeu Tavares Pacheco ,Antônio Pereira Júnior ,José Roberto S A Leite ,Adriana Sousa Rêgo ,Janaina Maiana Abreu Barbosa ,Flor De Maria Araújo Mendonça Silva

doi:10.7176/rhss/11-10-06

Jocélia Martins Cavalcante Dantas , Wellyson Da Cunha Araújo Firmo + Show 6 more

Open Access

https://doi.org/10.7176/rhss/11-10-06

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Abstract

Objective: To estimate the prevalence and socioeconomic characteristics of Chronic Kidney Disease (CKD) in first and second-degree relatives of patients on hemodialysis Method: A questionnaire was applied on socioeconomic conditions, lifestyle, and personal pathological background. The formula of CKD-EPI and/or proteinuria greater than or equal to 1+ was used to characterize CKD. Analysis using the logistic regression model. Results: 408 individuals were evaluated and 12% had CKD. 6.61% had a glomerular filtration rate (GFR) ≤ 60 mL / min / 1.73 m2 and 5.39% proteinuria in the urine. The variables associated with the presence of CKD were age (OR = 1,60; 95% IC = 1,31-1,96), PAS (OR: 1,69; 95% IC: 1,24-2,28), PAD (OR: 1,52; 95% IC: 1,18- 1,96) and blood glucose (OR: 2,03; 95% IC: 1,38-2,99). Conclusion: It is necessary to implement routines for systematic evaluation that prevent or delay the loss of renal function, in addition to measures that improve the pre-dialysis clinical conditions of this population. Keywords: Chronic kidney disease, Family, Glomerular filtration rate. DOI: 10.7176/RHSS/11-10-06 Publication date: May 31 st 2021

Highlights

With the aging of the population and the advent of cardiovascular diseases, many authors have considered chronic kidney disease (CKD) as the "millennium epidemic"
In Brazil, few studies have addressed the prevalence of CKD, especially if we consider those that used the criteria for defining CKD proposed by Kidney Disease Improving Global Outcomes (KDIGO)
When asked about the knowledge that this population had about CKD and hemodialysis and there is a high prevalence of non-knowledge about CKD (68.62%) and hemodialysis (52.45%) in the same way as the results found by Khalil and Abdalrahim (2014) in which about half of the study participants had no information about the pathology

Summary

Introduction

With the aging of the population and the advent of cardiovascular diseases, many authors have considered chronic kidney disease (CKD) as the "millennium epidemic". CKD is a serious global public health problem due to its increasing morbidity and mortality, incidence and prevalence, as well as high economic costs to health systems (Wen et al, 2014; Saran et al, 2017). As a nearly asymptomatic disease in its early stages, the actual prevalence of CKD is still unknown, even in countries like Japan and the United States (USA) that have a robust database on the pathology (Mills et al, 2015). In Brazil, few studies have addressed the prevalence of CKD, especially if we consider those that used the criteria for defining CKD proposed by Kidney Disease Improving Global Outcomes (KDIGO). Data from a systematic review that used studies with different methodologies for the diagnosis of CKD, including self-referral, found prevalences in Brazil that ranged from 1.43% to 27.20% (Marinho, Penha, Silva & Galvão, 2017)

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