Abstract
Early diagnosis of lung cancer helps to reduce the cancer death rate significantly. Over the years, investigators worldwide have extensively investigated many screening modalities for lung cancer detection, including computerized tomography, chest X-ray, positron emission tomography, sputum cytology, magnetic resonance imaging and biopsy. However, these techniques are not suitable for patients with other pathologies. Developing a rapid and sensitive technique for early diagnosis of lung cancer is urgently needed. Biosensor-based techniques have been recently recommended as a rapid and cost-effective tool for early diagnosis of lung tumor markers. This paper reviews the recent development in screening and biosensor-based techniques for early lung cancer detection.
Highlights
Lung cancer is a major health problem in the United State and worldwide [1]
This paper summarizes the recent achievements in screening and biosensor-based approaches for lung cancer detection
Biomarkers predict the response to certain types of therapy such as surgery and chemotherapy Biomarkers predict the response certain and types of therapy such as surgery and or or estimate the risk of future relapse.toGenetic proteomics-based biomarkers arechemotherapy two major types estimate the riskwhich of future
Summary
Lung cancer is a major health problem in the United State and worldwide [1]. Every year, approximately 1.3 million new lung cancer cases and about 1.2 million lung cancer deaths occur in Europe and North America [2,3,4]. Researchers have extensively studied lung screening methods, including chest radiograph (CRG), computed tomography (CT), low-dose CT (LDCT), magnetic resonance imaging (MRI), and positron emission tomography (PET). These techniques have some drawbacks, such as being expensive and having low sensitivity for identifying cancer cells at early stages. Radiations produced from CT increased the cancer risk [17] To solve this limitation, LDCT was applied for lung imaging and it reduced 20% of lung cancer mortality [18,19]. Various biosensors have been developed to analyze tumor markers for early diagnosis of various diseases including lung cancer [27,28,29,30]. The paper is structured as follows: Section 2 presents the current available lung screening approaches; Section 3 describes the MIT based approaches for imaging of biological objects; Section 4 reviews some recently developed biomarker and biosensor based techniques for lung cancer detection; Section 5 presents some current trends and future perspectives of lung cancer detection techniques; and Section 6 concludes this paper
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call