Abstract

a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.

Highlights

  • The neuronal cells encode information, conduct it, and send the information to different neurons or non-neuronal tissues.[21]

  • The hippocampus and medial prefrontal cortex are essential for the encoding and retrieval of episodic memories.[44,10,22,29]

  • Morris water maze test Twenty-four hours after the last administration, the experimental animals were subjected to Morris water maze (MWM) test in order to assess spatial learning and memory using Morris method.[40]

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Summary

Introduction

The neuronal cells encode information, conduct it, and send the information to different neurons or non-neuronal tissues.[21]. Determination of LD50 The LD50 of the Talinum triangulare leaves aqueous extract was established using the modified Lorke’s method.[38] Twenty-four adult Wistar rats (180-200g) were used for the first and second phases of the study. The rats were fasted overnight before administering orally 500, 1000, 2000 and 4000 mg/kg body weight of Talinum triangulare leaves aqueous extract to the groups respectively, for the first phase with no signs of toxicity and mortality for seventy-two hours post administration.

Results
Conclusion
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