Abstract
The present study was conducted to evaluate and compare on anatomical bases between the different types of nerve graft, autograft, collagen tubes (natural polymers), and acellular epineurial nerve sheaths (biological conduits), which included acellular rabbit nerve graft and acellular rat nerve graft.
 Fourty local breaded rabbits were used and divided into four groups, each of ten rabbits. Then each group was subdivided again into two subgroups according to time of scarifying, which was after 45 days and 3 months post operation.
 All animals were undergone surgical operation on the right thigh and sciatic nerve of 8-10mm section was sectioned at the mid thigh, and the gap was replaced with the previous graft types comparison was made between the right (experimental) and left thighs (control) side. Samples from proximal, middle and distal stumps were taken to evaluate the regeneration process.
 The gross results revealed that, most animals developed ulcer formation and others with bone exposure. All animal groups of both periods showed delay latency. All these manifestations appeared as a subsequent of Wallerian degeneration with effects of nerve graft guidance extra cellular matrix, Schwann-macrophage interactions, neurons death and surgical scarring.
 
 http://dx.doi.org/10.25130/tjps.25.2020.003
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