Schwannoma in the lower inner quadrant of the right breast in a male patient: A rare case report.

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Lower inner-quadrant breast schwannomas are exceedingly rare, with no reports of their occurrence in male patients in the literature. In this report, we describe a male patient with a schwannoma in the lower inner quadrant of the right breast. A 26-year-old man presented at our hospital with a 6-month history of a lump in the right breast and reported pain in the area 3 days prior to presentation. Ultrasonography identified a 0.86 × 0.64 cm hypoechoic nodule 0.41 cm beneath the skin in the lower inner quadrant of the right breast. The nodule exhibited clear boundaries and uniform internal echogenicity with no signs of significant blood flow on color Doppler flow imaging. The patient was concerned that the nodule was benign or malignant. Histopathological and immunohistochemical analyses after complete surgical excision confirmed that the lesion was breast schwannoma. The postoperative course was unremarkable and the tumor did not recur during 7 years of follow-up. Biochemical parameters were examined preoperatively. The radiological examination of breast color Doppler ultrasound was performed. A well-shaped, 0.86 × 0.64 cm mass, complete capsule in the lower inner quadrant of the right breast was surgically resected. The postoperative course was unremarkable and the tumor did not recur during 7 years of follow-up. Breast schwannoma is an extremely rare tumor that is very difficult to preoperatively diagnose. Preoperative biochemical examination and ultrasonography can only provide diagnostic ideas. Histological and immunohistochemical analyses are required for confirmation. It can transform into malignant peripheral nerve sheath tumors, but not often. Consequently, regular postoperative follow-up is required for such patients, especially ultrasonography.