Abstract

The genus, Naegleria, includes four species of amebae which are either free-living or opportunistic pathogens. Naegleria fowleri, is the causative agent of Primary Amebic Meningoencephalitis, a rare but almost always fatal disease in man. Naegleria australiensis is an environmental isolate which is moderately pathogenic in mice. Naegleria lovaniensis and Naegleria gruberi are nonpathogenic environmental isolates. The four species were examined by scanning electron microscopy in order to determine whether membrane surface extensions, called food cups, could be correlated to pathogenicity. Food cups have been previously identified on the surface of Entamoeba histolytica and N. fowleri. It has been suggested that the food cups or stomas, are associated with internationalization of liquid and particulate components.

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