SAT0002 ACPA-negative rheumatoid arthritis consists of two genetically distinct subsets based on RF positivity

Chikash Terao ,Etsuko Maruya ,Kazuhiko Yamamoto ,Keitaro Matsuo ,Masaki Katayama ,Shigeki Momohara ,Yuta Kochi ,Fumihiko Matsuda ,Shigeru Honjo ,Kota Shimada ,Hiroh Saji ,Koichiro Ohmura ,Akira Murasawa ,Asako Suzuki ,Kazuo Tajima ,K Ikari ,Hisashi Yamanaka ,Kiyoshi Takamatsu ,Ryo Yamada ,Tsuneyo Mimori

doi:10.1136/annrheumdis-2012-eular.2950

SAT0002 ACPA-negative rheumatoid arthritis consists of two genetically distinct subsets based on RF positivity

Chikash Terao , Etsuko Maruya + Show 18 more

https://doi.org/10.1136/annrheumdis-2012-eular.2950

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Journal: Annals of the Rheumatic Diseases

Publication Date: Jun 1, 2013

Affiliation: Center for Genomic Science, The University of Tokyo, Aichi Cancer Center, Kyoto University, Tokyo Women's Medical University, Institute of Rheumatology, Saiseikai Takaoka Hospital, National Sagamihara Hospital, Institute for Rheumatic Diseases (Japan), Dogo Onsen Hospital

#ACPA-negative Rheumatoid Arthritis #ACPA-negative Rheumatoid Arthritis Patients #ACPA-positive Rheumatoid Arthritis #Rheumatoid Arthritis #Anti-citrullinated Peptide/protein Antibody #ACPA-negative Patients #Shared Epitope #Rheumatoid Arthritis Patients #Specific HLA-DRB1 Alleles #Arthritis Rheum

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BackgroundHLA-DRB1, especially the shared epitope (SE), is strongly associated with rheumatoid arthritis (RA) [1]. However, recent studies have shown that SE is at most weakly associated with RA without anti-citrullinated...

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SAT0002 ACPA-negative rheumatoid arthritis consists of two genetically distinct subsets based on RF positivity