SAT-308 QUALITY OF LIFE IN ESRD PATIENTS ON MAINTENANCE HEMODIALYSIS FOR MORE THAN 7 YEARS IN A TERTIARY CARE CENTRE

Abstract

Assessment of quality of life (QOL) of patients with End-Stage Renal Disease (ESRD) on hemodialysis is very important. In this study, we aim to assess QOL in patients undergoing hemodialysis for a duration more than 7 years and evaluated the effects of various sociodemographic and clinico-laboratory factors affecting QOL of such patients in our dialysis centre in PSG Institute of Medical Science and Research, Coimbatore, Tamil Nadu, India. A cross-sectional study was conducted among 23 patients with ESRD undergoing hemodialysis at our dialysis centre for more than 7 years. Demographic data including age, sex, ethnicity, educational status, marital status, employment, income, duration of illness, duration of travel to dialysis centre and duration on hemodialysis were collected. Clinicolabratory data including native kidney disease, comorbidity, dialysis access, haemoglobin level, ferritin, TSAT, erythropoietin use and dose, albumin, calcium, phosphorous, PTH and viral serology were noted. QOL was assessed using the World Health Organization Quality of life (WHOQOL-BREF) questionnaire. Four domains (physical, psychological, social, and environmental) of the WHOQOL-BREF were the primary end points of this study. The relationship between sociodemographic factors, clinico-laboratory factors and QOL scores were analysed using independent samples t-test and one-way analysis of variance. In this study we found that the overall Quality of Life in chronic hemodialysis patient with respect to all four Domains were low. The mean of Domain 1 (Physical)- 50.2±12.5, Domain 2 (Psychological)- 55.8±13.1 , Domain 3 (Social)- 62.5±21.4 , Domain 4 (Environmental) - 60.7±14.5. There was statistically significant Domain 2 (Psychological) QOL in male patients. There was statistically significant Domain 4 (Environmental) QOL in age group between 41-60 years. Even though not statistically significant patient group with high income, employed, fistula access, haemoglobin more than 10 mg/dl and erythropoietin usage had marginally better QOL in all Domains. In this study of 23 patients on maintenance hemodialysis for more than 7 years, factors like aetiology of native kidney disease, dialysis through AV fistula, regular dialysis, water quality maintained according to AAMI standards and absence of cardiovascular disease are probably having an impact on long term survival.