SARS-COV-2 infection and pregnancy outcome: a cross-sectional study from eastern U.P. population, India

Abstract

Listen

Translate article

Pregnant females with severe COVID-19 are more likely to develop additional health problems as a result of the infection. This study evaluates and compares the clinical features and pregnancy outcomes among women with and without SARS-CoV-2 infection. Pregnant women were divided into two groups: those with SARS-CoV-2 infection and those without (control group). Blood samples were collected for a COVID panel, including D-Dimer, Ferritin, IL-6, CRP, and Procalcitonin (PCT). Additionally, oral nasal swabs were taken to assess the SARS-CoV-2 viral load. Both SARS-CoV-2 positive and negative women were monitored every trimester for any pregnancy-related complications. The study found that pregnant women infected with SARS-CoV-2 had significantly shorter gestation periods compared to their SARS-CoV-2 negative counterparts. There was also a notable increase in the rates of caesarean and pre-term deliveries among the SARS-CoV-2 positive group, indicating a higher incidence of these outcomes due to the infection. The present study highlights a significant correlation between SARS-CoV-2 infection in pregnant women and adverse pregnancy outcomes, such as reduced gestation periods, increased caesarean sections, and higher pre-term delivery rates. These findings highlight the need for vigilant monitoring and management of pregnant women with SARS-CoV-2 to mitigate risks and improve maternal and fetal health. Continued research is essential to understand these associations and develop targeted interventions to protect this vulnerable population.