Abstract

In clinical practice, a connection between the progression of osteoarthritis and the development of sarcopenia is frequently observed, but individual scientific studies provide conflicting results. Therefore, there is a need to conduct a comparative review and meta-analysis to assess the prevalence of sarcopenia in patients with knee osteoarthritis. Several databases from 2010 to 2023 were examined. Sarcopenia prevalence data were summarized using odds ratios (ORs) with their 95 % confidence intervals (CIs). A total of 504 articles were studied, which included 7,495 participants with a mean age of 68.4 years; 72.4 % were female. As a result, the prevalence of sarcopenia in patients with knee osteoarthritis was 45.2 %, while in the control group it was 31.2 %. The study found that the prevalence of sarcopenia in knee osteoarthritis was more than twice as high as in the control group (OR = 2.07; 95 % CI: 1.43–3.00; I2 = 85 %).

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