Salt, skeletons, and suicide. Focus on “Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton”

Abstract

Listen

Translate article

high NaCl and other sources of hypertonicity are cellular stresses that span evolution. A protective response common to most organisms is cellular accumulation of compatible organic osmolytes, driven by increased transcription of transporters and synthesizing enzymes. In mammalian cells the