Abstract
SALL4 gene is closely related to body malformations related diseases, embryonic stem cell development, and hematopoietic malignancies. SALL4 can activate hematopoietic stem cell through Wnt signaling pathways, and promote continued proliferation of leukemia stem cells, leading to leukemia. In-depth study of SALL4 gene and its protein function will help clarify the pathogenesis of leukemia, providing a new target for the treatment of leukemia. Key words: Genes,SALL4 ; Neoplasms ; Leukemia ; Stem cells ;
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have