Salivary Antioxidants Role in Oral Health and Diseases (A Review Article)

Abstract

Background: Saliva is the first defense system of the body through its antioxidant status (total antioxidant capacity), which is either enzymatic or non-enzymatic antioxidants, which block the process of oxidation by neutralizing free radicals; therefore, the objective of this review is to evaluate the role of salivary antioxidant biomarkers in the diagnosis and monitoring of many oral and periodontal diseases and related systemic disorders. Method: We searched for articles published on PubMed and Google Scholar in the last 20 years and then filtered the mints 60 papers according to the following keywords: saliva, total antioxidant capacity (TAC) and oxidative stress (OS). Conclusion: Saliva samples can be beneficial in demonstrating oxidant-antioxidant balance in oral and systemic illnesses and may be a suitable sample type in the diagnosis and monitoring of many pathologies in the body.