Abstract
Now, there are many chemicals in our environment. In addition, new chemicals over one thousand are coming in the world yearly. Therefore, impact of toxic chemicals coming from environment on human health is now the most important international problem. In this paper, we give the outline of guideline, which had been proposed recently in the Subcommitee on Chemical Substances, The Central Pharmaceutical Affairs Council, Japan, for testing of chemicals, and also describe the current state and problems on safety evaluation of chemicals.
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