Abstract
Safety and effectiveness of kidney transplantation using a donation-after-brain-death donor with acute kidney injury: a retrospective cohort study
Highlights
Kidney transplantation is the optimal choice for treating end-stage renal disease (ESRD) because it improves prognosis and quality of life compared with dialysis[1]
In an attempt to increase the donor pool for kidney transplantation, the American United Network for Organ Sharing suggested the use of expanded criteria donors (ECDs) in 2002, even though those donors have 1.7-fold higher graft failure compared with standard criteria donors (SCDs)[3]
We found that the delayed graft function (DGF) rate tended to increase with the donor acute kidney injury (AKI) stage
Summary
Kidney transplantation is the optimal choice for treating end-stage renal disease (ESRD) because it improves prognosis and quality of life compared with dialysis[1]. In an attempt to increase the donor pool for kidney transplantation, the American United Network for Organ Sharing suggested the use of expanded criteria donors (ECDs) in 2002, even though those donors have 1.7-fold higher graft failure compared with standard criteria donors (SCDs)[3]. Domagala et al.[10] reported finding no difference in the rate of biopsy-proven acute rejection (BPAR) episodes between donors with and without AKI in the first year post-transplantation. Those reports found no relationship between donors with AKI and graft survival[7,8,9,10].
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