Abstract
Childhood maltreatment accounts for 64% of the population attributable risk for addiction to illicit drugs. We previously reported that degree of drug use in maltreated individuals correlated with T2-relaxation time (T2-RT- an indirect measure of relative cerebral blood volume) in prefrontal regions and size of the lingula of the cerebellar vermis. A key question is whether there is a causal relation and if these measures could predict subsequent degree of use in a prospective longitudinal study.
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