Abstract

BackgroundSubstance use disorders are reliably associated with high impulsivity and sensation seeking. Importantly, both precede problematic substance use, implicating them as risk factors. Individuals with substance use disorders show variable degrees of substance use (combined quantity and frequency) and substance-related problems and differ in both aspects from healthy controls. Dimensional research has indicated differential associations of impulsivity-related traits as well as sensation seeking with the degree of substance use and substance-related problems. The current study aimed to clarify whether impulsivity-related traits and sensation seeking predict substance-related problems above and beyond the degree of substance use and are thus specifically linked to problems, the dimension that characterizes substance use disorders.MethodWe assessed impulsivity-related traits and sensation seeking using self-report, as well as delay discounting, a behavioral indicator of impulsivity, in a sample of 258 substance-using adults.ResultsSensation seeking and impulsivity-related traits significantly predicted the degree of substance use, with sensation seeking explaining the largest portion of variance. In contrast, self-reported impulsivity, in particular when experiencing negative emotions (urgency), but not sensation seeking or delay discounting, predicted substance-related problems when controlling for the degree of substance use.ConclusionsThis suggests that urgency, but not sensation seeking, may be specifically linked to substance-related problems and thus especially relevant for substance use disorders. Taken together, this study underlines the necessity to assess and control for the degree of substance use in risk factor research concerning substance-related problems. Thus, it may inform future research improving targeted prevention and therapy.

Highlights

  • Substance use disorders are reliably associated with high impulsivity and sensation seeking

  • Sensation seeking and impulsivity-related traits significantly predicted the degree of substance use, with sensation seeking explaining the largest portion of variance

  • Self-reported impulsivity, in particular when experiencing negative emotions, but not sensation seeking or delay discounting, predicted substancerelated problems when controlling for the degree of substance use

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Summary

Introduction

Substance use disorders are reliably associated with high impulsivity and sensation seeking. We are proposing a dimensional approach examining the associations of potential risk factors with substancerelated problems while statistically controlling for the degree of substance use. We assessed both variables separately and dimensionally in a population of substance users of varying degrees of substance use. Using this approach, we aimed to take a first step in reevaluating the role of impulsivity-related traits as risk factors for SUDs. High levels of impulsivity-related traits are robustly found in individuals with SUDs [2,3,4,5]. Controlling for the degree of use has been neglected in previous work

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