Abstract

Schizophrenia is characterized by self-disturbances, including impaired self-evaluation abilities and source monitoring. The core brain regions of the default-mode network (e.g. medial prefrontal cortex, precuneus) are known to play a key role in self-related processing. In theory, self-disturbances in schizophrenia may arise from impaired default-mode network activity. We performed a functional neuroimaging meta-analysis to verify this hypothesis.

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