Abstract

Structural brain deficits is linked to risk for suicidal behavior although findings are inconsistent to-date. This may be due to the heterogeneity of suicidal behavior, including variation in suicidal intent and lethality of the suicidal act. We hypothesized that depressed higher-lethality suicide attempters, who may more closely resemble suicide decedents, would have smaller prefrontal cortical (PFC) volume compared to depressed non-attempters.

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