İs Combined Acellular Collagen Matrix and High Tibial Osteotomy Treatment Effective In Osteochondral Defects? Preliminary Study

Abstract

Aim: In this study, we want to compare clinical and radiological results of 12 patient treated with acellular collagen matrix (ACM) and High Tibial osteotomy-cellular collagen matrix(ACM-HTO) combination.Method: In this study, we evaluated 12 patients with chondral lesion prospectively the years of between 2014- 2016 after ethical approval. Cartilage damage was diagnosed with MRI and cartilage degeneration volume was calculated with Mimics medical image processing software and axis deviation was diagnosed with ortho X-ray. Patients were divided into two groups. ACM only (Group 1) and ACM- HTO (Group 2). Results: ACM only group consists of 5 patients. Preoperative mean of chondral lesion volume was 77.11±137.5 (0.27-321.61). Post-operative mean Knee score was 175.20±24.4(150-203) and chondral lesion volume was 0.3±0.03(0-0.8). ACM-HTO group consists of 7 patients. Preoperative mean of chondral lesion volume was 112.72±239(0.27- 653). Post-operative mean of HSS score was 155±20.4(135-183) and chondral lesion volume was 0.26±0.09(0-0.69).Conclusion: According to these results, all patients’ HSS scores and Cartilage volume are increased, but there were no significant differences were found between two groups.