Abstract

Metformin and sulfonylureas, used for Type 2 Diabetes Mellitus (T2DM) have been associated with electrolyte and acid-base imbalances. These imbalances can result in complications such as hyperkalemia and cardiac impairments which are particularly problematic for colorectal cancer patients (CRC). We aim to quantify the risk for electrolyte and acid-base imbalances associated with metformin vs sulfonylurea use in elderly CRC patients with T2DM, where the question remains unexamined.

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