Abstract
Rotavirus vaccine: a promise for the future.
Highlights
Studies have shown that rotavirus-associated disease occurs round the year in tropical climates with no consistent seasonal variation, there may be more peaks in the dry, cool months, or winter months [11]
Safe and effective rotavirus vaccines are needed to reduce the enormous public-health burden associated with illness due to rotavirus, especially in developing countries [14]
The large global burden of healthcare due to rotavirus-associated disease in both developed and developing countries prompted the development of rotavirus vaccines
Summary
Studies have shown that rotavirus-associated disease occurs round the year in tropical climates with no consistent seasonal variation, there may be more peaks in the dry, cool months, or winter months [11]. Safe and effective rotavirus vaccines are needed to reduce the enormous public-health burden associated with illness due to rotavirus, especially in developing countries [14]. The large global burden of healthcare due to rotavirus-associated disease in both developed and developing countries prompted the development of rotavirus vaccines. The vaccine had an efficacy of 85-98% against severe rotavirus-associated disease requiring hospitalization and reduced all-cause hospitalizations by 42-59%, preventing most hospitalizations for rotavirus [17,18].
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