Rotavirüs Gastroenteritli Çocuklarda Nötrofil/ Lenfosit Oranı, Trombosit/Lenfosit Oranı Ve Ortalama Trombosit Hacminin Değerlendirilmesi

Abstract

ABSTRACT
 Rotavirus is most common agent responsible for acute gastroenteritis in Turkey as its in the world. There are no studies about the relationship between hematologic parameters and clinic of rotavirus gastroenteritis in children. The aim of this study is to compare the values of neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume in patients with rotavirus gastroenteritis with healthy controls. Patients with acute rotavirus gastroenteritis, who were admitted to our Department of Pediatric Health and Diseases between January 2016 and January 2017, were included in this study. Patients' data were reviewed, retrospectively. Age, gender, seasonal distribution, symptoms, duration of hospitalization, course of disease, type of acute gastroenteritis, frequency of nosocomial infections and complications were investigated. 210 patients diagnosed with rotavirus gastroenteritis were included in the study. 116 (55.2%) of the patients were male and 94 (44.8%) were female. The mean age of our patients was 39.09±17.64 months. There was no statistically significant difference between genders in terms of mean ages. Mean hospitalization time of patients was 3.75±2.03 days. In our study, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and mean platelet volume values were found statistically higher in patients with rotavirus-associated gastroenteritis than in healthy subjects. We think that these parameters will be indicative to predict the course of the disease and complications.