Prognostic value of elevated mean platelet volume in patients undergoing primary angioplasty for ST-elevation myocardial infarction

Abstract

Objective The aim of this study was to evaluate the prognostic value of mean platelet volume (MPV) in patients with STEMI undergoing primary percutaneous coronary intervention (PCI).Methods We prospectively enrolled 495 consecutive STEMI patients. The study population was divided into tertiles based on admission MPV values. The high MPV group (n = 148) was defi ned as a value in the third tertile (> 8.9), and the low MPV group (n = 347) included those patients with a value in the lower two tertiles (≤ 8.9). Clinical characteristics, in-hospital and six-month outcomes of primary PCI were analysed.Results Higher six-month all-cause mortality rates were observed in the high MPV group In Cox multivariate analysis; a high admission MPV value (> 8.9) was found to be a powerful independent predictor of six-month all-cause mortality.Conclusions These results suggest that a high admission MPV level was associated with increased six-month all-cause mortality in patients with STEMI undergoing primary PCI.