Abstract

Evidences of a favorable effect of statin treatment on arterial stiffness are accumulating, but not all studies have shown a positive effect on arterial stiffness [ [1] Tziomalos K. Athyros V.G. Karagiannis A. Mikhailidis D.P. Endothelial function, arterial stiffness and lipid lowering drugs. Expert Opin Ther Targets. 2007; 11: 1143-1160 Crossref PubMed Scopus (52) Google Scholar ]. In addition, the precise mechanisms of statin on arterial stiffness are poorly understood. Therefore, we examined the effects of short term rosuvastatin treatment on arterial stiffness as assessed with brachial-ankle (ba) PWV and their mechanisms in patients with hypercholesterolemia who had no additional cardiovascular risk factors.

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