Rosmarinus officinalis extract, complementary testing for quality control as active ingredient for formulations

Abstract

Today contemporary alternative medicine continues to increase significantly around the world. Taking the above into account and given the need for new pharmaceutical formulations, techniques for the extraction of bioactive compounds from plants have been developed, such is the case of the extract of rosemary (Rosmarinus officinalis). The purpose of this work is to evaluate, through official and unofficial tests from the Pharmacopeia of the United Mexican States, a rosemary extract tablet. The extract was obtained by maceration in methanol and a simple distillation. Subsequently, using the direct compression method, prepare tablets and then evaluate them and determine the identity, disintegration, dissolution, titration and dose uniformity tests established by the Pharmacopeia of the United Mexican States (from spanish Farmacopea de los Estados Unidos Mexicanos, FEUM) for this type of pharmaceutical presentations. The results show that the tablets comply with the determinations of the pharmacopeial tests, which indicates that the tablets prepared in this work are of good quality, from a manufacturing point of view and can pass the validation process, so they could be used in the clinic.