Rosa damascena leaf extract mediated palladium nanoparticles and their anti-inflammatory and analgesic applications

Abstract

Palladium nanoparticles (PdNPs) were synthesized by Rosa damascena leaf extract. The nanoparticles were characterized by UV–Vis spectroscopy, Fourier Transform Infrared spectroscopy (FTIR), X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM), and Dynamic Light Scattering (DLS) and Zeta Potential. Synthesized palladium nanoparticles were discovered to have approx 20–50 nm in a spherical shape. This eco-friendly synthesis of palladium nanoparticles exhibits biomedical applications. Rat models were used to check the activity of the palladium nanoparticles as anti-inflammatory and analgesic agents. Even though their efficacy was lower than standard drugs, palladium nanoparticles produced favorable results for both activities. This finding indicates that Rosa damascena leaf extract is an excellent bio-reductant for synthesizing palladium nanoparticles and has promise for various pharmacological and biological applications.