Rosa damascena flower mediated phytofabrication of palladium nanoparticles, in-vitro and in-vivo applications

Abstract

The formation of palladium nanoparticles is described in this research work as being simple, affordable, and non-toxic. This study employed Rosa damascena flower extract to effectively reduce ions to palladium nanoparticles. Biogenic formation of palladium nanoparticles (PdNPs) is characterized using Ultraviolet spectrophotometers, FTIR, XRD spectrophotometers, and TEM. The SPR peak was recorded at 360 nm in UV–visible analysis of biologically formed palladium nanoparticles. The diameter of the synthesized palladium nanoparticles was around approx 50 nm with a spherical shape. These biologically formed palladium nanoparticles demonstrated notable antibacterial activities. After antibacterial testing of palladium nanoparticles further check for anti-inflammatory and analgesic activity on rat model. These finding indicate that the flower extract of R.damascena is an excellent bio-reductant for the formation of palladium nanoparticles and has promise for employment in several fields in biomedical application.