ROS: Important factor in plant stem cell fate regulation

Abstract

Reactive oxygen species (ROS) are initially considered to be toxic byproducts of aerobic metabolic reactions. However, increasing evidence has shown that they have emerged as signaling molecules involved in several basic biological processes. Recent studies highlight the pivotal role of ROS in the maintenance of shoot and root stem cell niche. In this review, we discuss the impact of ROS distribution and their gradients on the stability of the stem cell niches (SCN) in shoot apical meristem (SAM) and root apical meristem (RAM) by determining the balance between stemness and differentiation. We also summarize several important transcription factors that are involved in the regulation of ROS balance in SAM and RAM, regulating key enzymes in ROS metabolism, especially SOD and peroxidase. ROS are also tightly interconnected with phytohormones in the control of the stem cell fate. Besides, ROS are also important regulators of the cell cycle in controlling the size of the stem cells. Understanding the regulation mechanisms of ROS production, polarization gradient distribution, homeostasis, and downstream signal transduction in cells will open exciting new perspectives for plant developmental biology.