Abstract
In plastic and reconstructive surgery, skin flaps are widely employed. Large wounds that cannot be closed with normal treatments are treated with skin flap surgery. Skin flap necrosis is a well-known post-flap cover issue that can affect cosmetic outcomes and patient satisfaction. Variable occurrence rates and inconsistent related factors have been reported in many retrospective studies of this condition. Despite advances in technology, the rate of flap necrosis remains significant in daily procedures. Topical Nitroglycerin (NTG) has shown potential in decreasing flap necrosis in several randomized trials. In this case study, we aim to evaluate the efficacy and safety of topical NTG in preventing flap failure.
Highlights
Skin flap necrosis is a well-known post-flap cover issue that can affect cosmetic outcomes and patient satisfaction
We aim to evaluate the efficacy and safety of topical NTG in preventing flap failure
The keystone flap is different from other loco-regional flaps in that it has a great capability for adaptability
Summary
Skin flap necrosis is a well-known post-flap cover issue that can affect cosmetic outcomes and patient satisfaction. Variable occurrence rates and inconsistent related factors have been reported in many retrospective studies of this condition. The rate of flap necrosis remains significant in daily procedures. Nitroglycerin relaxes vascular smooth muscle by acting as a vasodilator by producing nitric oxide [1]. Another wellknown benefit is that it has anti-thrombotic effects. Increased blood flow to the application region is achieved by increasing www.acquirepublications.org/JOP the caliber of the vasculature and ensuring its patency [2]. Topical Nitroglycerin (NTG) has shown potential in decreasing flap necrosis in several randomized trials. We aim to evaluate the efficacy and safety of topical NTG in preventing flap failure
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