Role of the Choroid in Automated Age-related Macular Degeneration Detection from Optical Coherence Tomography Images.

Abstract

Automatic detection of age-related macular degeneration (AMD) from optical coherence tomography (OCT) images is often performed using the retinal layers only and choroid is excluded from the analysis. This is because symptoms of AMD manifest in the choroid only in the later stages and clinical literature is divided over the role of the choroid in detecting earlier stages of AMD. However, more recent clinical research suggests that choroid is affected at a much earlier stage. In the proposed work, we experimentally verify the effect of including the choroid in detecting AMD from OCT images at an intermediate stage. We propose a deep learning framework for AMD detection and compare its accuracies with and without including the choroid. Results suggest that including the choroid improves the AMD detection accuracy. In addition, the proposed method achieves an accuracy of 96.78% which is comparable to the state-of-the-art works.