Abstract
Elucidation of the structure of LH-RH (Matsuo et al., 1971; Burgus et al., 1971) has opened new possibilities for studies of the factors involved in the control of LH and FSH secretion. This presentation will attempt to summarize the data describing the role of estrogens and androgens as specific and important modulators of gonadotropin secretion. Using the rat as model, evidence vill be presented of a specific action of these steroids at the hypothalamic and pituitary levels.
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