Abstract
A series of perfusion studies were made in which the capillary vessels of the frog's mesentery were kept under observation through the microscope. Striking differences were found between the circulation obtained with perfusates containing particulate matter and that obtained with similar solutions which were particle-free. Colloidal Ringer perfusates free of particulate matter did not fill all the vessels of the capillary bed, circulating only through the a-v capillaries. In a previous publication,1 it was pointed out that the a-v capillaries represent direct continuations of the arterioles and serve as bridging channels to the venules. The dye T-1824 (Evans blue, Eastman Kodak Co.) has been used for blood volume studies because of its poor diffusibility.2 When solutions containing Evans blue were used, the restriction of the color to the a-v capillaries stood out in contrast to the true capillaries which remained colorless. The addition of particulate matter, either as a fine suspension of carbon or of w...
Published Version
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