Abstract
Role of Oxidative Stress in Liver Health and Disease.
Highlights
ROS are not always the bad guy; important transcription factors such as Nrf2, NF-kB, and AP-1 are activated by H2O2-dependent oxidation of thiol residues
Oxidative stress can result from an increase in prooxidant formation or a decrease or deficiency in antioxidants
Due to the central role of oxidative stress on liver disease, this special issue was devoted to its implication in hepatic health and disease
Summary
ROS are not always the bad guy; important transcription factors such as Nrf2, NF-kB, and AP-1 are activated by H2O2-dependent oxidation of thiol residues. Editorial Role of Oxidative Stress in Liver Health and Disease D.F., Mexico 2Lipid Research Laboratory, VA Medical Center, 50 Irving Street NW, Washington, DC 20422, USA 3Department of Biochemistry and Molecular Medicine, The George Washington University, 2300 I Street NW, Suite 530, Washington, DC 20037, USA Correspondence should be addressed to Pablo Muriel; pmuriel@cinvestav.mx
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