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https://doi.org/10.1007/s10517-010-1052-7
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Cite Publication Date: Nov 25, 2010 | |
 Citations: 10 |
Affiliation: Pirogov Russian National Research Medical University
Whole-cell ionic currents through mechanically gated channels (MGC) were recorded in isolated cardiomyocytes under voltage clamp conditions. In unstrained cells, NO donors SNAP and DEA-NO activated MGC and induced MG-like currents. In contrast, in stretched cells with activated MGC, these NO-donors inactivated and inhibited MGC.
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