Abstract
Results The preliminary findings from the Cochrane Library found 28 trials out of the eligible 121 trials (excluding four pilot and feasibility studies) were found in a subsequent Cochrane systematic review. The weight of the included HTA trials varied widely (from 100% to 9%). In eight reviews, the trial had a weight of 100% indicating how the trial provided the only evidence for that particular comparison. However, of those 28 trials, only half showed superiority. For the rest, the 95% confidence interval included a measure of no difference. The implications of this will be discussed.
Highlights
The Health Technology Assessment programme relies partly on systematic reviews for the identification of topics for the commissioning of clinical trials
Aims and Objectives To review the HTA portfolio of published trials to determine the extent to which HTA funded trials are included in subsequent systematic reviews
The impact of a new trial on the subsequent systematic review is not examined. By completing this side of the loop can it be established whether further research is required
Summary
The Health Technology Assessment programme relies partly on systematic reviews for the identification of topics for the commissioning of clinical trials. Role of NIHR HTA clinical trials on subsequent systematic reviews From 3rd International Clinical Trials Methodology Conference Glasgow, UK. Background The Health Technology Assessment programme relies partly on systematic reviews for the identification of topics for the commissioning of clinical trials.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call