Abstract
The literature data indicate that the impaired expression of some types of metalloproteinases can result from different causes, both endogenous and exogenous. A modern notion of the role of matrix metalloproteinases in the processes of placental angiogenesis is analyzed. There was used literature research method according to the database PubMed for 19942021. The study of the activity and function of metalloproteinases in various gestational complications associated with the formation of primary placental insufficiency could have helped to search the diagnostic markers of these disorders.
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