Role of Madhuka Pushpa in Sandhana Kalpana; microbiological pharmaceutico-analaytical study

Abstract

Introduction: Sandhana kalpana are unique alcoholic formulations using natural sources of drugs as ingredients. Flowers of Madhuka(Madhuka indica Gmel)(wet/dry)are added as fermentative initiators in many such asva- arishta preparations. But exact role of these flowers was not well studied or documented scientifically. Hence a study designed to prove evidences for these facts. Materials and Methods: Fresh and dry sample of test drug was taken and microbiological study was conducted to explore their microflora. Three samples of Madhukasava was prepared as per classical references, adding fermentative initiators as fresh flowers, dried flowers and not adding any flowers and a comparative analytical study of these samples conducted. Results: Microflora extraction delineated that dry flowers contain more yeast colonies than that of fresh flowers. Phramceutico- analytical study has shown better parameters form the point of total sugar, total solids and total alchohol among fresh and dry flower groups. Conclusion: Overall result emphasizes the fact that Madhuka flowers have definite role in sandhana kalpana and dried ones with more yeast colonies have proved better than fresh flowers.