Abstract

Background: The metabolic syndrome is defined by the clustering of risk factors that predisposes people to diabetes and cardiovascular disease (CVD. MetS had a high (58%) prevalence of dyslipidemia, and increasing age, greater BMI, central obesity, hypertension, and high blood glucose levels have been found as independent predictors of dyslipidemia.
 Aim of the Work: This study aimed to role of lipid profile and fasting blood glucose in metabolic syndrome.
 Subjects and Methods: The research was carried out at the Index Medical College and Research Center in Indore, in the Department of Biochemistry. A total of 120 people with metabolic syndrome and 120 healthy controls were included in the study. A blood sample was taken from the anticubital vein and centrifuged to obtain serum, which was then evaluated for lipid profile and FBS levels quantitatively. Result and Conclusion: Present study suggested that the FBG is the most critical factor in MS, and all aspects of the lipid profile have significant relationships with MS.
 Keywords: Metabolic syndrome, fasting blood glucose

Highlights

  • Background: The metabolic syndrome is defined by the clustering of risk factors that predisposes people to diabetes and cardiovascular disease

  • The World Health Organization (WHO), the International Diabetes Federation (IDF), and other international agencies agreed on the term "metabolic syndrome" as the best way to describe this nosologic entity

  • Table-1 Shows statistical analyzes projected that the cholesterol, triglycerides, LDL and HDL found to be significantly. This was observed that the average cholesterol, triglycerides, LDL and HDL concentration that was found in the control group was 190.56 ± 13.10, 148.88 ± 7.75, 70.61 ± 2.74 and 50.67 ± 4.24, in the MetS group, it was 256.14 ± 14.34, 230.51 ± 7.52, 134.46 ± 2.61 and 27.74 ± 2.61 and in the DM group, it was 271.88 ± 14.44, 246.35 ± 10.90, 137.01 ± 3.43 and 33.56 ± 3.38

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Summary

Introduction

The metabolic syndrome is defined by the clustering of risk factors that predisposes people to diabetes and cardiovascular disease (CVD) 1, 2. Obesity, high blood pressure, and dyslipidemia are the key features of the syndrome. As a significant modifiable factor of cardiovascular disease and type-2 diabetes, it is increasingly garnering the attention of international research organizations and scientific organisations[3,4,5]. The MetS abbreviation has recently been used to replace the term Metabolic Syndrome. The World Health Organization (WHO), the International Diabetes Federation (IDF), and other international agencies agreed on the term "metabolic syndrome" as the best way to describe this nosologic entity

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