Abstract
BackgroundFiberoptic bronchoscopy and medical thoracoscopy are basic interventional modalities for the diagnosis of a wide variety of pleuropulmonary diseases. In some cases, we need fast and accurate results for decision-making. We aimed to evaluate the diagnostic accuracy of imprint cytology and its added value to the pulmonologist.ResultsMultiple biopsies were taken from 54 patients included 31 patients with lung masses subjected to fiberoptic bronchoscopy and 23 patients with undiagnosed exudative pleural effusion subjected to medical thoracoscopy. Imprint cytology was done to all biopsies which are later examined histopathologically. Regarding fiberoptic bronchoscopy biopsies, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of imprint cytology were 93.33, 100, 100, 33.33, and 93.55%, respectively. While in medical thoracoscopy biopsies, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of imprint cytology were 94.74, 100, 100, 80, and 95.65%, respectively.ConclusionImprint cytology is an easy, rapid, and reliable method that has a high sensitivity and specificity in the diagnosis of lung and pleural malignancies compared with histopathology.
Highlights
Fiberoptic bronchoscopy and medical thoracoscopy are basic interventional modalities for the diagnosis of a wide variety of pleuropulmonary diseases
Different bronchoscopic techniques are used for the diagnosis of lung cancer such as histological examination of specimens obtained by bronchial biopsies biopsy and cytological examination procedures such as bronchial washing, brushing, and needle aspiration
The 54 patients were classified into two groups: the bronchoscopic group included 31 patients aged more than 18 years who were subjected to fiberoptic bronchoscopy after clinical and radiological suspicion of bronchogenic carcinoma by both clinical and radiological findings
Summary
Fiberoptic bronchoscopy and medical thoracoscopy are basic interventional modalities for the diagnosis of a wide variety of pleuropulmonary diseases. In order to evaluate the wide variety of pulmonary and pleural diseases, we can use different endoscopic modalities as fiberoptic bronchoscopy and medical thoracoscopy which can provide us with valuable specimens for accurate diagnosis. Different bronchoscopic techniques are used for the diagnosis of lung cancer such as histological examination of specimens obtained by bronchial biopsies biopsy and cytological examination procedures such as bronchial washing, brushing, and needle aspiration Some combinations of these techniques have been reported to increase the diagnostic sensitivity for lung cancer compared with that of bronchial biopsy alone [1]. Histopathological results of pleural biopsies are not available at the time of the procedure, and in order to perform talc poudrage, the physician needs high clinical confidence of a malignant diagnosis [8]
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