Abstract
Abstract Background: Metalaxyl is a fungicide used to control soil-borne fungal diseases on fruits, cotton, soy bean, peanuts and grasses. Food contamination with metalaxyl is a worldwide problem especially in
Highlights
Metalaxyl is a benzenoide fungicide that widely used in developing countries; it is used to protect crops against soil-borne pathogens [1]
Metalaxyl had pathological effects on the structure of rat’s liver and these effects were decreased by ginger
Liver sections of control group examined by electron microscope showed hepatocytes with euchromatic nuclei, mitochondria, cisternae of rough and smooth endoplasmic reticulum (Figure 4)
Summary
Metalaxyl is a benzenoide fungicide that widely used in developing countries; it is used to protect crops against soil-borne pathogens [1]. Metalaxyl was reported to have cytogenetic effects on human and animal chromosomes in vitro [5] and Demsia et al, [6]. Reproductive toxicity of metalaxyl and mancozeb in adult male albino rat was detected by Rao et al, [8] and Mehra et al, [9]. Recent published studies have reported that metalaxyl toxicity may be associated with the enhanced production of reactive oxygen species (ROS).
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