Abstract
The novel coronavirus disease (COVID-19) has entered a threatening stage all over the world. Many lives have been lost, and many more are in need of treatment. The mild symptoms may include fever and dry cough, but in severe cases, it could lead to pneumonia and ultimately death in some instances. Though medical scientists all over the globe are working hard to develop a treatment for this disease, yet no definite cure has been found. To date, the treatment strategy is based on adopting strategies to break the transmission of the virus and repurposing of the old drugs to prevent the loss of life. Among the various potent candidates, flavonoids may play a protective role in these times. Studies have already proven various health-promoting properties of flavonoids in earlier viral diseases, like SARS and MERS. Since ancient times, been plants have used to treat a number of human diseases. Different phytoproducts have been previously described to inhibit the replication of numerous viruses. Despite the positive reports for plant-based medications, no successful clinical trials on phytoproducts as anti-COVID agents have been conducted to date. This review highlights the efficacy of flavonoids as a treatment strategy either alone or in combination with other drugs.
Highlights
The year 2020 observed one of the deadliest pandemics that has threatened the global health, security and economy [1]
It was rapidly shown to be caused by a novel coronavirus, causing severe acute respiratory syndrome [2]
The number of people infected with the severe Acute Respiratory Syndrome (ARD) associated with COVID-19 is rapidly increasing worldwide [3]
Summary
The year 2020 observed one of the deadliest pandemics that has threatened the global health, security and economy [1]. It was rapidly shown to be caused by a novel coronavirus, causing severe acute respiratory syndrome [2]. The number of people infected with the severe Acute Respiratory Syndrome (ARD) associated with COVID-19 is rapidly increasing worldwide [3]. The WHO Emergency Committee declared a global health emergency based on growing case notification rates at Chinese and international locations on January 30th, 2020 [4]. According to the current records of WHO reported on August 23rd, 2020, globally there are 23,057,288 confirmed cases of COVID-19, including a high death toll of 800,906. In India, the pandemic broke around January 2020, increasing leaps and bounds in the following months. The data showed that the cured/discharged individuals accounted for a good 2338035
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