Role of demographic and dietary factors in predicting Gall Bladder Carcinoma

Abstract

Introduction: Carcinoma of the gallbladder (GBC), is the most common cancer of the biliary tree. It is also one of the most highly malignant tumours. The aetiology of the carcinoma gall bladder is poorly understood. Chronic cholecystitis and gallstones, choledochal cysts, female gender, old age and exposure to carcinogens are some of the factors implicated in the causation of gall bladder cancer. The current changes in lifestyles of individuals about indulgence in unhealthy fat-rich food, lack of exercise, obesity, sedentary lifestyles and the high incidence of gall bladder carcinoma in Bihar, focused our attention on gall bladder carcinoma and its etiological factors. Methodology: An analytical case-control study was conducted to study the various etiological factors causing carcinoma of the gall bladder in patients of various regions of Bihar coming to PMCH Patna. A total of 101 cases of gall bladder carcinoma and a total of 101 patients without any gall bladder disease in the control group were included in the study.