Abstract
Aim: Recent studies dealing with metabolic syndrome (MS) and related complications has been focused on brown adipose tissue (BAT), because depots of this tissue has been lately found in adult humans and because of its ability to degrade energetic substrates. However, the exact role of BAT in the pathogenesis of MS remains unclear. Here we study age-related changes of interscapular BAT (iBAT) activity of non-obese model of dyslipidemia and metabolic syndrome - hereditary hypertriglyceridemic rats (HHTg) in comparison with control rats Wistar. We further analyzed the effect iBAT extirpation on metabolic syndrome-related disorders.
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