Abstract
Antibiotics are an extremely valuable addition to the armamentarium available to health practitioners for management of bacterial infections. Due to the potential risk of adverse systemic effects of systemic applications and ineffectiveness of systemic antibiotics in the necrotic pulpless tooth and the periradicular tissues, local application of antibiotics will be more effective since it is directly acting against the microorganism in the infected root canal. This paper reviews the applications of antibiotics and antibiotics containing medicaments in endodontics.
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