Abstract
Cryogenic correlative light and electron microscopy seeks to leverage orthogonal information present in two powerful imaging modalities. Recent advances in cryogenic electron microscopy (cryo-EM) allow for the visualization of structures within cells at the nanometer scale. While cryo-EM provides exquisite spatial resolution, it lacks information on the cellular environment that influences the observed structures. Fluorescence microscopy can be used to recover this information when specific labels are used.
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