Abstract
Objective To investigate the safety and efficiency of robot-assisted partial nephrectomy (RAPN) for totally intrarenal tumors (TITs). Methods Thirty-eight patients who underwent RAPN for treating TITs by one experienced surgeon were included between August 2012 and December 2017. There were 25 males and 13 females, aged 26-72 years(mean 51.6 years). Tumors of 24 cases were in right kidney, and 14 cases in left kidney. The diameter of tumor was(3.12±0.92)cm, the R. E.N.A.L. score was(9.76±1.00), and the Scr was(74.82±20.32)μmol/L. Patients’ peri-operative and oncological outcomes were analyzed. Results All the tumors were successfully resected without conversion to open surgery or radical nephrectomy. Mean operative time and ischemia time were (188.47±46.75) min and (24.32±7.69) min. Mean blood loss was (115.79±43.66) ml. One-week postoperative Scr was (85.97±28.33) μmol/L. Postoperative hemorrhage was successfully treated by DSA or drug therapy in 3 patients. The pathological examination showed 28 clear cell renal cell carcinomas, 3 chromophobe renal cell carcinomas, 3 TFE-3 infusion related renal cell carcinomas, 2 metanephric adenomas, 1 acidophile adenoma and 2 angioleiomyolipomas. One positive surgical margin occurred in RAPN group for cystic components. No evidence of tumor progression observed during follow-up. Conclusions RAPN is safe and effective in treating TITs when performed by an experienced surgeon at a high-volume institution. Further prospective and large-scale study was warranted to evaluate the long-term outcomes. Key words: Kidney neoplasms; Partial nephrectomy; Totally intrarenal tumors; Robot
Published Version
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