Abstract

RNA Editing Minireview Series

Highlights

  • What are the biochemical mechanisms responsible for RNA editing? The two minireviews in this issue focus on the genetic and biochemical aspects of nucleotide substitution RNA editing by deamination, either A-to-I [8] or C-to-U [9]

  • Minireview: RNA Editing Minireview Series editing machinery that carry out deamination editing of the A-to-I variety

  • Davidson entitled “C-to-U RNA Editing: Mechanisms Leading to Genetic Diversity,” summarizes progress in understanding the biochemical mechanisms and substrate targets for C-to-U RNA editing in mammals [9]

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Summary

Introduction

The two minireviews in this issue focus on the genetic and biochemical aspects of nucleotide substitution RNA editing by deamination, either A-to-I [8] or C-to-U [9]. The substrates and enzymes responsible for these editing processes are reviewed, along with the functional roles that representative editing events play in cellular processes.

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