Rivea hypocrateriformis Plant Extract Mediated Synthesis of ZnO Nanoparticles: Characterization, Antioxidant and Anticancer Activities

Abstract

Nanomedicine has emerged as a promising approach for cancer diagnosis and treatment. This study explores the green synthesis of zinc oxide nanoparticles using Rivea hypocrateriformis extract. The synthesized ZnO nanoparticles were characterized through UV-vis, FT-IR, zeta potential, XRD, SEM with EDS and TEM analyses. These nanoparticles were also evaluated for their impact on A549 cell lines. The UV visible spectroscopy identified absorbance peaks, while FT-IR analysis detected various functional groups. SEM and XRD images confirmed the partial crystal spherical form and crystal nature. The cytotoxicity assessments revealed an enhanced cytotoxic effect, marking a significant step toward synthesizing ZnONPs as potential anticancer agents. This research suggests the potential of these nanoparticles as chemo-preventive agents in future cancer treatments, in addition to their strong antioxidant properties.