Risk of overestimating loss of cerebral autoregulation-author's reply.

Abstract

Editor—We read with great interest the correspondence from Claudia Niño and colleagues about our paper ‘Impact of impaired cerebral blood flow autoregulation on electroencephalogram signals in adults undergoing propofol anaesthesia: a pilot study’.1 Their main concern is that the number of patients with impaired cerebral autoregulation (CA) may have been overestimated. They point to a possible difference in prevalence of comorbidities between the preserved CA group (CA+, mean flow index, Mxa <0.3) and the impaired CA group (CA−, Mxa ≥0.3).